Generic name: Valacyclovir hydrochloride
Brand names: Valtrex
Why is Valtrex prescribed?
Valtrex is used to treat certain herpes infections, including herpes zoster (the painful rash known as shingles), genital herpes, and herpes cold sores on the face and lips.
Most important fact about Valtrex
Valtrex should not be used by anyone with a weak immune system, such as those with HIV infection or those who have undergone a bone marrow or kidney transplant. Valtrex can cause serious side effects, including death, in such people.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Valtrex.
- More common side effects may include:
Abdominal pain, aggressive behavior, agitation, allergic reactions, coma, confusion, decreased consciousness, depression, diarrhea, dizziness, facial swelling, hallucinations, headache, hepatitis, high blood pressure, joint pain, mania, menstrual problems, nausea, rapid heartbeat, rash, visual abnormalities, vomiting
Why should Valtrex not be prescribed?
Avoid Valtrex if you are sensitive to it or the similar drug acyclovir (Zovirax).
Special warnings about Valtrex
High doses of Valtrex have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant.
If your kidneys are not functioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Valtrex can make your condition worse or affect your central nervous system (brain and spinal cord).
Effects on the central nervous system are more common in older adults, leading to such symptoms as agitation, confusion, and hallucinations. Their kidneys are also more likely to be affected; and those with kidney problems need a smaller dose. In addition, older adults tend to suffer the pain of shingles for a longer time after healing has begun.
Valtrex relieves the symptoms of genital herpes, but it is not a cure. There's also no evidence that it will prevent transmission of the disease. To avoid spreading the infection, don't have sexual intercourse during a flare-up.
Valtrex is not intended for use in children.
Possible food and drug interactions when taking Valtrex
If you are taking Valtrex with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Valtrex with cimetidine (Tagamet) and/or probenecid (Benemid).
Special information if you are pregnant or breastfeeding
The effects of Valtrex during pregnancy and breastfeeding have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately. If you are nursing and need to use Valtrex, your doctor may advise you to discontinue breastfeeding while using the medication.
